My 2 year old female quaker, Chewy, has always been very close to me and my wife. Especially me. She always comes to me over my wife. But when I came home from work yesterday, and tried to let her out of her cage, like I do every day, she bit me and became very defensive and I couldn't get near her. So I left the cage door open and she came out on her own. When my wife came home, I warned her of Chewy's behavior. But Chewy was fine with her. Let her pick her up, love on her, everything like normal. But I still can't get close to her. We took her to have her pin feathers removed, wings clipped and nails trimmed today, for which she was due. And we hoped that would make a difference. It did for a while. But after that pampering, she's always kind of tranquil for a few hours. And after a few hours, she's back to attacking at me. We called back to the place where we have her boarded when we are out of town, and she said another quaker owner called her this afternoon, who said his female quaker was suddenly doing the same to him. Is this a hormone thing? Anyone have any suggestions on what to do? Or will it just go away?

Is it possible they changed Quakers on you? If they gave you the other person's Quaker by accident, it could be because she doesn't know you, and ditto for the Quaker in the other person's house.

Nope. She only goes to boarding when we go outta town and we haven't been outta town for months but the place also cuts her wings and trims her nails and stuff. I took her outta her cage that morning like I always do and played with her and she was fine but when I got home she has been in attack mode. She has always let me do anything with her and now she want let me near her

Moody ...maybe PMS don`t ever take a bit from your fid as personal..
They are not domesticated as cats and dogs and therefor carry some wild traites who knows what has caused this just be your ever loving self and she may settle down ...give her a few treats as you take he out of the cage ...
Good luck ..

Do you have a mirror in the cage? I don't know at what age, but Pepper got really territorial around that time. Before that I could put my hand down into her cage but I certainly don't anymore. She's fine if she is away from the cage, but not if she is on it or near it. I have a basket that I hold up to the door and she steps on it and then I hold it away while I reach in. She is never locked in. She plays in the cage, on the cage and on the floor under the cage with her toys.